Papillary carcinoma of the thyroid

Causes and Risks:
The cause is unknown, but radiation may be a contributing factor. Thyroid function tests are usually normal. Risk factors are radiation therapy to the head or neck and being over 40. The incidence is higher among women.

Other types of thyroid cancer are anaplastic carcinoma of the thyroid , follicular tumor of the thyroid , medullary carcinoma of thyroid , thyroid lymphoma , and metastatic thyroid cancer. The incidence is 1 out of 1,000 people. Papillary carcinoma is rare in children. More than 90% of pediatric-age thyroid cancers are well-differentiated follicular carcinomas .

Prevention:
unknown

Symptoms:
  • enlargement of thyroid gland or swelling in neck



Signs and Tests:
A physical examination reveals enlarged cervical lymph nodes. An examination of the thyroid reveals single or multiple nodules .



Treatment:
Surgical removal of the thyroid gland ( thyroidectomy ) is the initial treatment . Radiation therapy with radioactive iodine may follow surgery. Thyroid replacement therapy may be needed after surgery.

Prognosis:
Many papillary carcinomas are not associated with a high degree of malignancy . Many people have a normal life expectancy if a diagnosis is made early.

Complications:

  • Surgical risks involve inadvertent removal of the parathyroid glands, or damage to nerve tissue of the larynx, which leads to serious complications.
  • Rarely, spreading of cancer to lymph nodes or through blood vessels to other sites ( metastasis ) occurs.



Call Your Healthcare Provider:
Call for an appointment with your health care provider if symptoms of this disorder occur.

Call for an appointment with your health care provider if you have had a thyroidectomy and new symptoms develop, including muscle twitching, cramps, or changes in your voice.


The endocrine system is the chemical control center of the body. The pituitary gland is often considered the master control; sending out hormones that regulate the function of the thyroid, adrenal glands, ovaries, and testis. Over- or under-production of hormones from any of these glands is associated with many different types of disease.




This CT scan of the upper chest (thorax) shows a malignant thyroid tumor (cancer). The dark area around the trachea (marked by the white U-shaped tip of the respiratory tube) is an area where normal tissue has been eroded and died (necrosis) as a result of tumor growth.




This CT scan shows a thyroid cancer tumor in the throat, encircling, narrowing, and displacing the windpipe (trachea).




This special scan (scintiscan) shows enlargement of the thyroid gland and extension behind the breastbone (retrosternal space). The false color image was generated by a computer during a radioisotope (I-131) thyroid scan.