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Von Willebrand's disease Causes and Risks:
Von Willebrand's disease is the most common hereditary bleeding disorder. It is transmitted by an autosomal gene and affects both sexes. Most cases are mild and bleeding may occur after a surgical procedure or tooth extraction. The condition is worsened by the use of aspirin and other nonsteroidal anti-inflammatory drugs. Bleeding may decrease during pregnancy .
The disease is estimated to occur in 3 or 4 people per 100,000. There are no racial or ethnic associations with this disorder. A family history of a bleeding disorder is the primary risk factor.
Prevention:
There is no known prevention.
Symptoms:
Signs and Tests:
Note: The trait can be identified with genetic testing and counseling.
This disease may also alter the results of the following tests:
Treatment:
No treatment is usually required because bleeding is mild. However, if trauma occurs or surgery is scheduled, cryoprecipitate or desmopressin acetate can be given to raise the levels of von Willebrand factor, which will decrease the tendency towards bleeding . Fresh plasma may also be used to decrease bleeding.
Children with von Willebrand's disease should avoid unnecessary trauma, and those with severe disease should avoid contact sports. During menstruation, adolescent females may want to take extra precautions to avoid embarrassing accidents. During bleeding episodes, elevate and apply cold compresses and gentle pressure to the area. During nosebleeds , apply pressure over the bridge of the nose, and have the child lean forward to prevent blood running down the back of the throat and being swallowed.
Prognosis:
Females giving birth usually do not experience excessive bleeding .
Bleeding problems begin early in life and decrease with age: life span is usually normal. Since this disease is genetically transmitted, genetic counseling may be recommended for parents.
Complications:
Postoperative hemorrhage ( bleeding ) may occur.
Call Your Healthcare Provider:
Call your health care provider if bleeding occurs with no reason.
If you have this disorder and are scheduled for surgery or are in an accident, be sure to notify the health care providers about your condition.
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