Factor V deficiency

Causes and Risks:
Normal blood coagulation is a complex process involving as many as 20 different plasma proteins , which are known as blood coagulation factors. A series of complex chemical reactions using these factors takes place very rapidly to form an insoluble protein called fibrin that stops bleeding . When certain coagulation factors are deficient or missing, the chain reaction does not take place normally. In this disorder, bleeding ranges from mild to severe. The disease is similar to hemophilia , except bleeding into joints is uncommon. Bleeding can occur almost anywhere in the body, and death from hemorrhage has occurred with this disorder. Excessive bleeding with menstrual periods and postpartum hemorrhage occurs frequently. A family history of a bleeding disorder is a risk factor. men and women are affected equally.

Prevention:
This is an inherited disorder; there is no known prevention.

Symptoms:



Signs and Tests:



Treatment:
Fresh plasma or fresh frozen plasma infusions will correct the deficiency temporarily and should be given daily during a bleeding episode.

Support Groups:
The stress of illness can often be helped by joining a support group where members share common experiences and problems. See hemophilia - support group .

Prognosis:
The probable outcome is good with diagnosis and proper treatment.

Complications:
Hemorrhage could occur.

Call Your Healthcare Provider:
Go to the emergency room or call the local emergency number (such as 911) if you have an unexplained or prolonged loss of blood.