Factor X deficiency

Causes and Risks:
Normal blood coagulation is a complex process involving as many as 20 different plasma proteins , which are known as blood coagulation factors. A series of complex chemical reactions using these factors takes place very rapidly to form an insoluble protein called fibrin that stops bleeding . When certain coagulation factors are deficient or missing, the chain reaction does not take place normally. In Factor X disorder, bleeding ranges from mild to severe. Women may have severe menstrual bleeding and postpartum hemorrhage. The incidence ranges from 1 out of 500,000 to 1 out of 1,000,000 people. Newborns may present with prolonged bleeding after circumcision.

Prevention:
This is a rare inherited disorder; there is no known way to prevent it.

Symptoms:



Signs and Tests:



Treatment:
The bleeding disorder is corrected by infusions of fresh frozen plasma or factor X concentrates during acute episodes.

Support Groups:
The stress of illness can often be helped by joining a support group where members share common experiences and problems. See hemophilia - support group .

Prognosis:
The loss of blood may be life threatening.

Complications:
Severe bleeding or hemorrhage can occur.

Call Your Healthcare Provider:
Call your health care provider, go to the emergency room, or call the local emergency number (such as 911) if you have an unexplained or severe loss of blood.