Waterhouse-Friderichsen Syndrome


Necrosis can occur any time there is abnormal coagulation within the blood vessels. In this person, all circulation to the toes and front part of the foot has ceased and gangrene has developed in the toes. This condition in infants may follow infection with meningococci, generalized sepsis, and disseminated intravascular coagulation.




Purpura is a condition characterized by bleeding into the skin or other tissue. Purpura fulminans is a rapidly progressive form of purpura. It usually occurs in children and frequently results in death. This picture shows a critically ill child with purpura fulminans on the lower extremities.




Meningococcemia is a life-threatening infection that occurs when the bacteria, Neisseria meningitidis, invades the blood stream. There is usually bleeding into the skin ( petechiae and purpura). The tissue may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring.




Meningococcemia is a life-threatening infection that occurs when the bacteria, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) usually occurs and the tissue may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring.