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HELLP syndrome Causes and Risks: HELLP syndrome occurs in approximately 10% of pregnant women with pre-eclampsia or eclampsia . It may occur long before a pregnancy reaches term (for example, HELLP at 30 weeks gestation). HELLP may occur without an associated elevation of blood pressure . Frequently, the syndrome is misdiagnosed as hepatitis , gallbladder disease , idiopathic thrombocytopenic purpura , or thrombotic thrombocytopenic purpura . Prevention: Early and continuing prenatal care to facilitate early identification and treatment of conditions such as pre-eclampsia and eclampsia may help to prevent the disorder. Symptoms: Signs and Tests: Examination shows upper abdominal tenderness , especially in the right upper quadrant. The liver may be enlarged. Liver function tests (liver enzyme tests) may be abnormal. Treatment: Delivery of the infant is essential because liver function rapidly deteriorates in this condition. Prognosis: High neonatal death (20 to 25%), usually because of prematurity , is associated with this condition. Complications: Hemorrhage may occur within the mother's liver. Permanent liver damage may occur if delivery is delayed. Call Your Healthcare Provider: Call your health care provider or obstetrician if symptoms occur during pregnancy . HELLP syndrome can rapidly progress to an emergency condition!
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