Barrett's esophagus

Causes and Risks:
Irritation of the lining of the esophagus by gastric acid secretions is the probable cause. The condition occurs more frequently in men than women. Risk factors are gastroesophageal reflux . An increased risk of developing cancer of the esophagus is present with this condition.

Prevention:
Diagnosis and treatment of gastroesophageal reflux may prevent the onset of Barrett's esophagus.

Symptoms:



Signs and Tests:
Looking at the esophagus with an endoscope and obtaining a sample of esophagus tissue for examination (esophagoscopy with biopsy ) reveals Barrett's esophagus.

Treatment:
Treatment includes general measures to control gastroesophageal reflux , medications, and surgery.

General measures include:

  • weight reduction
  • avoiding lying down after meals
  • sleeping with the head of the bed elevated
  • taking medication with plenty of water
  • avoiding dietary fat , chocolate, caffeine , and peppermint because they may cause lower esophageal pressure
  • avoiding alcohol and tobacco

Medications to relieve symptoms and control gastroesophageal reflux include antacids after meals and at bedtime, Histamine H2 receptor blockers, cholinergic agents, and pro motility agents.

Surgery to remove a portion of the esophagus (resection of the esophagus) may be indicated if a biopsy shows the type of cellular changes that tend to lead to cancer (dysplasia).

Prognosis:
An increased risk of esophageal cancer is present. Follow-up endoscopy to look for dysplasia or cancer is often advised.

Complications:



Call Your Healthcare Provider:
Call for an appointment with your health care provider if symptoms of heartburn or painful swallowing persist for longer than a few days.

Call for an appointment with your health care provider if symptoms worsen, do not improve with treatment, or if new symptoms develop in a person with Barrett's esophagus.


This illustration shows the major organs of the digestive system. Their relative sizes and positioning in the body are also demonstrated.