Simian crease

Considerations:
Prominent creases, called flexion creases, normally appear on the palms of the hands and soles of the feet as part of the hand print and foot print. The palm normally has three flexion creases. Sometimes, the two horizontal creases fuse to form a single crease, called a single palmar crease or a simian crease.

Many structures develop in the first few months of gestation . Palmar creases develop early. Abnormalities in palmar creases may indicate the presence of other associated abnormalities. A single palmar crease or simian crease appears normally in approximately 1 out of 30 people.

Common Causes:

Note: There may be other causes of a simian crease. This list is not all inclusive, and the causes are not presented in order of likelihood. The causes of this symptom can include unlikely diseases and medications. Use the Symptom Analysis option to explore the possible explanations for a simian crease, occurring alone or in combination with other problems.

What to expect at your health care provider's office:
An infant with a simian crease generally has other symptoms and signs that, when taken together, define a specific syndrome or condition. Diagnosis of that condition is based on a family history, medical history, and thorough physical evaluation.

Medical history questions documenting a simian crease in detail may include:

  • Is there a family history of Down syndrome or other disorder associated with a simian crease?
  • Have other family members had a simian crease and no other abnormality?
  • What was the pregnancy like?
  • Did the mother use alcohol while pregnant ?
  • What other symptoms or physical abnormalities are also present?

Note: This finding is usually discovered by the health care provider.

The history and physical examination findings will determine whether further laboratory and diagnostic procedures are necessary.

After seeing your health care provider:
You may want to add a diagnosis related to a simian crease to your personal medical record.