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Estriol - urine How the Test is Performed:
A 24-hour urine sample is needed.
The health care provider will instruct you, if necessary, to discontinue drugs that may interfere with the test. - On day 1, urinate into the toilet upon arising in the morning.
- Collect all subsequent urine (in a special container) for the next 24-hours.
- On day 2, urinate into the container in the morning upon arising.
- Cap the container. Keep it in the refrigerator or a cool place during the collection period. Label the container with your name, the date, the time of completion, and return it as instructed.
Deliver it to the laboratory or your health care provider as soon as possible upon completion.
How to Prepare:
Consult the health care provider about factors that can interfere with the test, including an urinary tract infection .
Drugs that can increase test measurements include to adrenocorticosteroids (corticosteroids), estrogen-containing drugs, phenothiazines, and tetracyclines
Drugs that can decrease test measurements include clomiphene, ampicillin, and thyroxine.
How it Feels:
The test involves only normal urination, and there is no discomfort.
Risks:
There are no risks.
Why this Test is Performed:
The most common use of estriol measurements is in the evaluation of fetal status during pregnancy . Serial urine and/or blood studies for estriol excretion provide an objective means of assessing placental function and fetal normality in high-risk pregnancies.
Estriol is a specific type of estrogen hormone. Most often, total estrogen (estriol, estradiol, and estrone) is measured. However, sometimes the individual components may be measured.
Normal Values:
Excretion of estriol increases around the eighth week of gestation and continues to rise until shortly before delivery. Rising values indicate an adequately functioning "fetoplacental unit" (fetus, placenta, and all associated structures).
male: 1.0 to 11.0 mcg/24-hours
female follicular: 0 to 14 mcg/24-hours
female ovulatory: 13 to 54 mcg/24-hours
female luteal: 8 to 60 mcg/24-hours
female post-menopausal: 0 to 11 mcg/24-hours
pregnancy (first trimester): 0 to 800 mcg/24-hours
pregnancy (second trimester): 800 to 12,000 mcg/24-hours
pregnancy (third trimester): 5,000 to 50,000 mcg/24-hours
Note: mcg/24-hours = micrograms per 24-hours
Abnormal Results:
Greater-than-normal estriol levels may indicate Decreasing values suggest fetoplacental deterioration.
Lower-than-normal estriol levels may indicate
Cost:
The estimated cost is $25 to $60.
Special Considerations:
Estrogen testing is considered to be about 90% accurate in evaluating ovary function.
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