Tensilon Test

How the Test is Performed:
An IV is started, then the drug Tensilon is introduced slowly. The health care provider may want to fatigue the muscles by having you do various exercises such as counting to 100 until your voice diminishes, or holding your arms above your shoulders until they drop. The rest of the Tensilon is given. You will then be asked to perform some repetitive muscular movements like crossing and uncrossing your legs. You are observed for improved muscle strength. The test may be repeated. Additional Tensilon may be given to help differentiate between myasthenia gravis and other conditions.

How to Prepare:
There may be no preparations, however you should follow any diet or other directions from the health care provider.

How it Feels:
There will be a sharp prick as the IV needle is inserted. There may be some side effects from the drug.

Risks:
The risks are side effects from the drug, including respiratory failure.

Why this Test is Performed:
The test helps diagnosis myasthenia gravis , may aid in differentiation between myasthenic and cholinergic crises, and may be used to monitor oral anticholinesterase therapy.

Normal Values:
The muscles respond to the Tensilon in the normal ways.

Abnormal Results:
In myasthenia gravis , the muscles will improve immediately following the Tensilon. The maximum benefit only lasts several minutes. In myasthenic crisis (exacerbation of the disease that requires anticholinesterase therapy), there is a brief improvement in the muscle strength. In cholinergic crisis (overdose of anticholinesterase), the Tensilon will exaggerate the muscle weakness .

Additional conditions under which the test may be performed:



Cost:
The estimated cost is $30 to $40.

Special Considerations:
Not applicable.